diff --git a/api_routes/drug-disease.json b/api_routes/drug-disease.json new file mode 100644 index 00000000..79576fb5 --- /dev/null +++ b/api_routes/drug-disease.json @@ -0,0 +1,5002 @@ +[ + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0018616", + "name": "central serous chorioretinopathy" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0021667", + "name": "neuralgia" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "UMLS:C3854347", + "name": "Intentional product misuse" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "UMLS:C3805175", + "name": "Appendicolith" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0002203", + "name": "constipation disorder" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0043726", + "name": "multiple organ dysfunction syndrome" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0009688", + "name": "myasthenia gravis" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0005113", + "name": "bacterial infectious disease" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0800175", + "name": "cardiogenic shock" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0000190", + "name": "ventricular fibrillation" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0017291", + "name": "reversible cerebral vasoconstriction syndrome" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0005649", + "name": "appendicitis" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0005298", + "name": "osteoporosis" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0005420", + "name": "hypothyroidism" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0005083", + "name": "psoriasis" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0003014", + "name": "rhinitis" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0005441", + "name": "otitis media" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0005709", + "name": "common cold" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0005961", + "name": "sinusitis" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0005108", + "name": "viral infectious disease" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0000740", + "name": "adenoid hypertrophy" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0004425", + "name": "hyperthyroidism" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0005044", + "name": "hypertensive disorder" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0005015", + "name": "diabetes mellitus" + } + }, + { + "drug": { + "id": "CHEBI:10082", + "name": "xylometazoline" + }, + "disease": { + "id": "MONDO:0005267", + "name": "heart disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0001358", + "name": "bronchial disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005146", + "name": "post-traumatic stress disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0006731", + "name": "drug-induced akathisia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "UMLS:C0001969", + "name": "Alcoholic Intoxication" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005383", + "name": "panic disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0002025", + "name": "psychiatric disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005618", + "name": "anxiety disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0004681", + "name": "learning disability" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0002494", + "name": "substance-related disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0007743", + "name": "attention deficit-hyperactivity disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0004456", + "name": "cocaine abuse" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005530", + "name": "opiate dependence" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0002134", + "name": "physiological sexual disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0001106", + "name": "kidney failure" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0004985", + "name": "bipolar disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005567", + "name": "substance withdrawal syndrome" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005804", + "name": "hyperprolactinemia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0100192", + "name": "liver failure" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0007774", + "name": "hyperreflexia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0001286", + "name": "exotropia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "UMLS:C0011609", + "name": "Drug Eruptions" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005302", + "name": "attention deficit hyperactivity disorder, inattentive type" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0004985", + "name": "bipolar disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0022578", + "name": "childhood bladder carcinoma" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005105", + "name": "melanoma" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0006732", + "name": "drug-induced dyskinesia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005178", + "name": "osteoarthritis" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0002009", + "name": "major depressive disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0002032", + "name": "colon carcinoma" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0021063", + "name": "malignant colon neoplasm" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0002277", + "name": "arteriosclerosis disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0007803", + "name": "multiple system atrophy" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005311", + "name": "atherosclerosis" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0011122", + "name": "obesity disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005146", + "name": "post-traumatic stress disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "UMLS:C0027055", + "name": "Myocardial Reperfusion Injury" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0002909", + "name": "hyperglycemia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0007263", + "name": "cardiac rhythm disease" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005010", + "name": "coronary artery disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005148", + "name": "type 2 diabetes mellitus" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005466", + "name": "hypersomnia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005383", + "name": "panic disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005300", + "name": "chronic kidney disease" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005015", + "name": "diabetes mellitus" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005395", + "name": "movement disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "UMLS:C0525041", + "name": "Neurobehavioral Manifestations" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005302", + "name": "attention deficit hyperactivity disorder, inattentive type" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0002342", + "name": "chondromalacia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005468", + "name": "hypotensive disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0004992", + "name": "cancer" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005091", + "name": "severe acute respiratory syndrome" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005047", + "name": "infertility disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0007743", + "name": "attention deficit-hyperactivity disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0007661", + "name": "Tourette syndrome" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0002909", + "name": "hyperglycemia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005192", + "name": "exocrine pancreatic carcinoma" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005362", + "name": "erectile dysfunction" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0000837", + "name": "bone resorption disease" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0018608", + "name": "pure autonomic failure" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0001384", + "name": "myopia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0007254", + "name": "breast cancer" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0000947", + "name": "psychosexual disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0009831", + "name": "malignant pancreatic neoplasm" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005043", + "name": "hyperplasia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0008903", + "name": "lung cancer" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0003709", + "name": "agoraphobia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005359", + "name": "drug-induced liver injury" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0000494", + "name": "renal fibrosis" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005362", + "name": "erectile dysfunction" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005072", + "name": "neuroblastoma" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0001247", + "name": "social phobia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005469", + "name": "orthostatic hypotension" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0000190", + "name": "ventricular fibrillation" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0001942", + "name": "generalized anxiety disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005180", + "name": "Parkinson disease" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0000437", + "name": "cerebellar ataxia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005578", + "name": "arthritic joint disease" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005052", + "name": "irritable bowel syndrome" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0001076", + "name": "glucose intolerance" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0011122", + "name": "obesity disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0007263", + "name": "cardiac rhythm disease" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0005618", + "name": "anxiety disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0043839", + "name": "ulcer disease" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0011918", + "name": "anxiety" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0024644", + "name": "myocardial ischemia" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0021107", + "name": "narcolepsy" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": "MONDO:0004985", + "name": "bipolar disorder" + } + }, + { + "drug": { + "id": "CHEBI:10093", + "name": "yohimbine" + }, + "disease": { + "id": 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}, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0001165", + "name": "tongue disorder" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0005292", + "name": "colitis" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "UMLS:C0919980", + "name": "VIIth nerve palsy" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0002471", + "name": "bursitis" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0005071", + "name": "nervous system disorder" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0003159", + "name": "vascular hemostatic disease" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0002909", + "name": "hyperglycemia" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0006547", + "name": "exanthem" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0003799", + "name": "conjunctivitis" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0004848", + "name": "ulcerative stomatitis" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0002610", + "name": "purpura" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0005469", + "name": "orthostatic hypotension" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0004980", + "name": "atopic eczema" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "UMLS:C0340865", + "name": "Anaphylactoid Reaction" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0002657", + "name": "breast disorder" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0005083", + "name": "psoriasis" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0013600", + "name": "insomnia" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0005351", + "name": "anorexia nervosa" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "UMLS:C0403632", + "name": "Non-Infectious Cystitis" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0006771", + "name": "glossitis" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0004247", + "name": "peptic ulcer disease" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "UMLS:C0233494", + "name": "Tension" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "UMLS:C2047937", + "name": "Ill-defined disorder" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0019337", + "name": "autoimmune bullous skin disease" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0005328", + "name": "eye disorder" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0004565", + "name": "intestinal obstruction" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0100053", + "name": "anaphylaxis" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0004730", + "name": "speech disorder" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0002102", + "name": "cheilitis" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "UMLS:C0233414", + "name": "Disturbance of attention" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0015691", + "name": "hypereosinophilic syndrome" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0000736", + "name": "dyschromatosis universalis hereditaria" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0005279", + "name": "pulmonary embolism" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0005137", + "name": "nutritional disorder" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "UMLS:C0151547", + "name": "Cataract specified" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0005178", + "name": "osteoarthritis" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0005578", + "name": "arthritic joint disease" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0043303", + "name": "hyperacusis" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0001152", + "name": "amnestic disorder" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0004843", + "name": "pathologic nystagmus" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "UMLS:C0340464", + "name": "Premature Cardiac Complex" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0023557", + "name": "infective vaginitis" + } + }, + { + "drug": { + "id": "CHEBI:10102", + "name": "zaleplon" + }, + "disease": { + "id": "MONDO:0008698", + "name": "achalasia" + } + } +] \ No newline at end of file diff --git a/api_routes/routes.js b/api_routes/routes.js index 4e8f55c3..53dd100e 100644 --- a/api_routes/routes.js +++ b/api_routes/routes.js @@ -10,6 +10,7 @@ const services = require('./services'); const external_apis = require('./external'); const samples = JSON.parse(fs.readFileSync(path.join(__dirname, './sample-query-cache.json'))); +const drugDiseasePairs = JSON.parse(fs.readFileSync(path.join(__dirname, './drug-disease.json'))); router.use('/', external_apis); @@ -58,6 +59,11 @@ router.route('/quick_answer') } }); +router.route('/explore') + .post(async (req, res) => { + res.status(200).send(drugDiseasePairs); + }); + router.route('/answer') .post(async (req, res) => { const { questionId, ara } = req.query; diff --git a/src/App.jsx b/src/App.jsx index 72f2bda2..a32c1f9f 100644 --- a/src/App.jsx +++ b/src/App.jsx @@ -11,6 +11,7 @@ import Guide from '~/pages/Guide'; import Tutorial from '~/pages/Tutorial'; import TermsofService from '~/pages/TermsofService'; import QueryBuilder from '~/pages/queryBuilder/QueryBuilder'; +import Explore from '~/pages/Explore'; import Answer from '~/pages/answer/Answer'; import QuestionList from '~/pages/questionList/QuestionList'; @@ -72,6 +73,9 @@ export default function App() { + + + diff --git a/src/components/header/Header.jsx b/src/components/header/Header.jsx index de5152b8..58097a17 100644 --- a/src/components/header/Header.jsx +++ b/src/components/header/Header.jsx @@ -14,6 +14,7 @@ export default function Header() {
Question Builder + Explore About Guide Tutorial diff --git a/src/pages/Explore.jsx b/src/pages/Explore.jsx new file mode 100644 index 00000000..10def6eb --- /dev/null +++ b/src/pages/Explore.jsx @@ -0,0 +1,160 @@ +import { Button, makeStyles } from '@material-ui/core'; +import { ArrowRight } from '@material-ui/icons'; +import React from 'react'; +import { + Grid, Row, Col, +} from 'react-bootstrap'; +import { useHistory } from 'react-router-dom'; +import QueryBuilderContext from '~/context/queryBuilder'; +import useQueryBuilder from './queryBuilder/useQueryBuilder'; + +const useStyles = makeStyles({ + hover: { + '& .MuiButtonBase-root': { + visibility: 'hidden', + }, + '&:hover .MuiButtonBase-root': { + visibility: 'visible', + }, + }, +}); + +const fetchPairs = async () => { + const res = await fetch('/api/explore', { method: 'POST' }); + if (!res.ok) throw new Error(res.statusText); + return res.json(); +}; + +export default function Explore() { + const [pairs, setPairs] = React.useState([]); + const [isLoading, setIsLoading] = React.useState(true); + + // eslint-disable-next-line no-unused-vars + const [error, setError] = React.useState(null); + + const queryBuilder = useQueryBuilder(QueryBuilderContext); + const history = useHistory(); + + const handleStartQuery = (pair) => { + const query = { + message: { + query_graph: { + nodes: { + n0: { + name: pair.disease.name, + ids: [pair.disease.id], + }, + n1: { + name: pair.drug.name, + ids: [pair.drug.id], + }, + }, + edges: { + e0: { + subject: 'n0', + object: 'n1', + predicates: [ + 'biolink:related_to', + ], + }, + }, + }, + }, + }; + + queryBuilder.dispatch({ type: 'saveGraph', payload: query }); + history.push('/'); + }; + + const classes = useStyles(); + + React.useEffect(() => { + let ignore = false; + + (async () => { + try { + const data = await fetchPairs(); + + if (ignore) return; + + setPairs(data); + setIsLoading(false); + } catch (e) { + setError(e.message); + setIsLoading(false); + } + })(); + + return () => { + ignore = true; + }; + }, []); + + return ( + + + +

Drug - Disease Pairs

+

+ These drug-disease pairs were generated using a machine learning model to align with the nodes + in the ROBOKOP knowledge graph. They highlight potential associations between various drugs and + a broad range of diseases, suggesting possible avenues for further research. These connections + can serve as a starting point for a new query by hovering over a pair and clicking “Start a Query”. +

+ +
+ + {isLoading ? 'Loading...' : ( + + + + + + + + + { + pairs.map((pair, i) => ( + + + + + + )) + } + +
+

Disease

+ 		+

Drug

+
+ {pair.disease.name} + {pair.disease.id} + + {pair.drug.name} + {pair.drug.id} +
+ )} + + + + ); +} + +function Chip({ children }) { + return ( + + {children} + + ); +}