How to calculate x5t#S256 from X509 cert in v4.x?

[suside]

In 2.x it's just:
jose.JWK.asKey(certPem)['x5t#S256']

[panva]

How to calculate x5t#S256 from X509 cert in v4.x?

You need to do the calculation yourself. In node that's very simple

import { X509Certificate } from 'node:crypto';

const thumbprint = Buffer.from(new X509Certificate(crt).fingerprint256.replaceAll(':', ''), 'hex').toString('base64url');